{"id":1043,"date":"2018-10-23T13:05:16","date_gmt":"2018-10-23T11:05:16","guid":{"rendered":"https:\/\/triton.u707.jussieu.fr\/hepatherWPpreprod\/?page_id=1043"},"modified":"2019-02-20T13:54:37","modified_gmt":"2019-02-20T12:54:37","slug":"objectifs","status":"publish","type":"page","link":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/la-cohorte\/description-de-la-cohorte\/objectifs\/","title":{"rendered":"Objectifs"},"content":{"rendered":"<p>La cohorte ANRS CO22 Hepather a pour objectif de d\u00e9crire l&rsquo;\u00e9volution \u00e0 long terme des infections chroniques par le Virus de l&rsquo;H\u00e9patite C &#8211; VHC, et le virus de l&rsquo;H\u00e9patite B &#8211; VHB, et identifier les <b>facteurs de pronostic<\/b> associ\u00e9s, y compris les biomarqueurs.<\/p>\n<p>Elle vise \u00e0 comparer l&rsquo;<b>efficacit\u00e9 <\/b><b>clinique<\/b> et la <b>s\u00e9curit\u00e9 des traitements<\/b> dans la \u00ab\u00a0vraie vie\u00a0\u00bb afin de d\u00e9terminer, au niveau du patient, ceux qui seront le plus susceptibles d&rsquo;am\u00e9liorer la sant\u00e9 globale et de limiter l&rsquo;apparition de r\u00e9sistances.<\/p>\n<p>Elle contribuera \u00e0 \u00e9laborer des strat\u00e9gies de traitement et de prise en charge des infections chroniques par le VHC et le VHB en termes de <b>co\u00fbt-efficacit\u00e9.<br \/>\n<\/b><br \/>\nElle constituera une <b>plateforme<\/b> pour la r\u00e9alisation d&rsquo;essais cliniques ou des recherches sur des biomarqueurs dans des sous-populations cibl\u00e9es.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>La cohorte ANRS CO22 Hepather a pour objectif de d\u00e9crire l&rsquo;\u00e9volution \u00e0 long terme des infections chroniques par le Virus de l&rsquo;H\u00e9patite C &#8211; VHC, et le virus de l&rsquo;H\u00e9patite B &#8211; VHB, et identifier les facteurs de pronostic associ\u00e9s, y compris les biomarqueurs. Elle vise \u00e0 comparer l&rsquo;efficacit\u00e9 clinique et la s\u00e9curit\u00e9 des traitements [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":165,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"jetpack_post_was_ever_published":false,"footnotes":""},"class_list":["post-1043","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Objectifs - ANRS CO22 HEPATHER<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/la-cohorte\/description-de-la-cohorte\/objectifs\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Objectifs - ANRS CO22 HEPATHER\" \/>\n<meta property=\"og:description\" content=\"La cohorte ANRS CO22 Hepather a pour objectif de d\u00e9crire l&rsquo;\u00e9volution \u00e0 long terme des infections chroniques par le Virus de l&rsquo;H\u00e9patite C &#8211; VHC, et le virus de l&rsquo;H\u00e9patite B &#8211; VHB, et identifier les facteurs de pronostic associ\u00e9s, y compris les biomarqueurs. Elle vise \u00e0 comparer l&rsquo;efficacit\u00e9 clinique et la s\u00e9curit\u00e9 des traitements [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/la-cohorte\/description-de-la-cohorte\/objectifs\/\" \/>\n<meta property=\"og:site_name\" content=\"ANRS CO22 HEPATHER\" \/>\n<meta property=\"article:modified_time\" content=\"2019-02-20T12:54:37+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/la-cohorte\/description-de-la-cohorte\/objectifs\/\",\"url\":\"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/la-cohorte\/description-de-la-cohorte\/objectifs\/\",\"name\":\"Objectifs - ANRS CO22 HEPATHER\",\"isPartOf\":{\"@id\":\"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/#website\"},\"datePublished\":\"2018-10-23T11:05:16+00:00\",\"dateModified\":\"2019-02-20T12:54:37+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/la-cohorte\/description-de-la-cohorte\/objectifs\/#breadcrumb\"},\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/la-cohorte\/description-de-la-cohorte\/objectifs\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/la-cohorte\/description-de-la-cohorte\/objectifs\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Accueil\",\"item\":\"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"La cohorte\",\"item\":\"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/la-cohorte\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Description de la cohorte\",\"item\":\"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/la-cohorte\/description-de-la-cohorte\/\"},{\"@type\":\"ListItem\",\"position\":4,\"name\":\"Objectifs\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/#website\",\"url\":\"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/\",\"name\":\"ANRS CO22 HEPATHER\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-FR\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/#organization\",\"name\":\"IPLESP UMRS 1136\",\"url\":\"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/i0.wp.com\/triton.iplesp.upmc.fr\/hepather_ANRS\/wp-content\/uploads\/2019\/02\/logoTagline_anrs_white.png?fit=464%2C175&ssl=1\",\"contentUrl\":\"https:\/\/i0.wp.com\/triton.iplesp.upmc.fr\/hepather_ANRS\/wp-content\/uploads\/2019\/02\/logoTagline_anrs_white.png?fit=464%2C175&ssl=1\",\"width\":464,\"height\":175,\"caption\":\"IPLESP UMRS 1136\"},\"image\":{\"@id\":\"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Objectifs - ANRS CO22 HEPATHER","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/la-cohorte\/description-de-la-cohorte\/objectifs\/","og_locale":"fr_FR","og_type":"article","og_title":"Objectifs - ANRS CO22 HEPATHER","og_description":"La cohorte ANRS CO22 Hepather a pour objectif de d\u00e9crire l&rsquo;\u00e9volution \u00e0 long terme des infections chroniques par le Virus de l&rsquo;H\u00e9patite C &#8211; VHC, et le virus de l&rsquo;H\u00e9patite B &#8211; VHB, et identifier les facteurs de pronostic associ\u00e9s, y compris les biomarqueurs. Elle vise \u00e0 comparer l&rsquo;efficacit\u00e9 clinique et la s\u00e9curit\u00e9 des traitements [&hellip;]","og_url":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/la-cohorte\/description-de-la-cohorte\/objectifs\/","og_site_name":"ANRS CO22 HEPATHER","article_modified_time":"2019-02-20T12:54:37+00:00","twitter_card":"summary_large_image","twitter_misc":{"Dur\u00e9e de lecture estim\u00e9e":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/la-cohorte\/description-de-la-cohorte\/objectifs\/","url":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/la-cohorte\/description-de-la-cohorte\/objectifs\/","name":"Objectifs - ANRS CO22 HEPATHER","isPartOf":{"@id":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/#website"},"datePublished":"2018-10-23T11:05:16+00:00","dateModified":"2019-02-20T12:54:37+00:00","breadcrumb":{"@id":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/la-cohorte\/description-de-la-cohorte\/objectifs\/#breadcrumb"},"inLanguage":"fr-FR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/la-cohorte\/description-de-la-cohorte\/objectifs\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/la-cohorte\/description-de-la-cohorte\/objectifs\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Accueil","item":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/"},{"@type":"ListItem","position":2,"name":"La cohorte","item":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/la-cohorte\/"},{"@type":"ListItem","position":3,"name":"Description de la cohorte","item":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/la-cohorte\/description-de-la-cohorte\/"},{"@type":"ListItem","position":4,"name":"Objectifs"}]},{"@type":"WebSite","@id":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/#website","url":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/","name":"ANRS CO22 HEPATHER","description":"","publisher":{"@id":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"fr-FR"},{"@type":"Organization","@id":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/#organization","name":"IPLESP UMRS 1136","url":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/","logo":{"@type":"ImageObject","inLanguage":"fr-FR","@id":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/#\/schema\/logo\/image\/","url":"https:\/\/i0.wp.com\/triton.iplesp.upmc.fr\/hepather_ANRS\/wp-content\/uploads\/2019\/02\/logoTagline_anrs_white.png?fit=464%2C175&ssl=1","contentUrl":"https:\/\/i0.wp.com\/triton.iplesp.upmc.fr\/hepather_ANRS\/wp-content\/uploads\/2019\/02\/logoTagline_anrs_white.png?fit=464%2C175&ssl=1","width":464,"height":175,"caption":"IPLESP UMRS 1136"},"image":{"@id":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/#\/schema\/logo\/image\/"}}]}},"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/PaQKc4-gP","jetpack-related-posts":[{"id":1047,"url":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/la-cohorte\/description-de-la-cohorte\/volontaires\/","url_meta":{"origin":1043,"position":0},"title":"Volontaires","author":"admin_ft","date":"23 octobre 2018","format":false,"excerpt":"Nombre de sujets pr\u00e9vus : L\u2019effectif pr\u00e9vu est de 25000 patients dont 15000 infect\u00e9s r\u00e9cents ou anciens par le VHC (dans la mesure du possible, moins de 10% des patients inclus avec r\u00e9ponse virologique soutenue \u00e0 l'inclusion et plus de 50% de patients na\u00effs de traitement dirig\u00e9 contre le VHC)\u2026","rel":"","context":"Article similaire","block_context":{"text":"Article similaire","link":""},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":2819,"url":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/projets-valides-par-le-cs\/","url_meta":{"origin":1043,"position":1},"title":"Projets valid\u00e9s par le CS","author":"admin_ft","date":"7 f\u00e9vrier 2019","format":false,"excerpt":"Projets en cours Stratification of Hepatocellular carcinoma risk using Biomarkers (STHEPBIO): Genome-based HCC-risk assessment models and sequential serum biomarkers for prediction and early detection of liver cancer Coordonnateur : Pierre Nahon N\u00b0 de CS de soumission : 20 Date CS : 12\/12\/2018 Epid\u00e9miologie clinique des lymphomes associ\u00e9s \u00e0 une h\u00e9patite\u2026","rel":"","context":"Article similaire","block_context":{"text":"Article similaire","link":""},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":165,"url":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/la-cohorte\/description-de-la-cohorte\/","url_meta":{"origin":1043,"position":2},"title":"Description de la cohorte","author":"admin_fchau","date":"24 janvier 2018","format":false,"excerpt":"La cohorte ANRS CO22 Hepather a \u00e9t\u00e9 lanc\u00e9e \u00e0 l\u2019initiative de l\u2019ANRS - France Recherche Nord & Sud Sida-hiv H\u00e9patites, de l\u2019Inserm - Institut national de la sant\u00e9 et de la recherche m\u00e9dicale et de l\u2019Afef - Association Fran\u00e7aise pour l\u2019\u00c9tude du Foie. Elle consiste \u00e0 \u00e9tudier les h\u00e9patites B\u2026","rel":"","context":"Article similaire","block_context":{"text":"Article similaire","link":""},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":188,"url":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/espace-patients\/les-etudes-en-cours\/","url_meta":{"origin":1043,"position":3},"title":"Les \u00e9tudes valid\u00e9es par le Conseil scientifique","author":"admin_fchau","date":"24 janvier 2018","format":false,"excerpt":"\/ A MODIFIER \/ Liste des PRS acad\u00e9miques valid\u00e9s : Etude de la qualit\u00e9 de vie des patients affect\u00e9s d'une h\u00e9patite C chronique suivis en\u00a0 consultation hospitali\u00e8re Coordonnateur : Yazdan Yazdanpanah Date de validation : Observatoire national de la r\u00e9sistance du virus de l'h\u00e9patite C aux antiviraux directs (DAA) Les\u2026","rel":"","context":"Article similaire","block_context":{"text":"Article similaire","link":""},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/triton.u707.jussieu.fr\/hepatherWPpreprod\/wp-content\/uploads\/2019\/01\/pictos_avancement_etude-1-e1546595305448.png?resize=350%2C200&ssl=1","width":350,"height":200},"classes":[]},{"id":1049,"url":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/la-cohorte\/description-de-la-cohorte\/methodologie\/","url_meta":{"origin":1043,"position":4},"title":"M\u00e9thodologie","author":"admin_ft","date":"23 octobre 2018","format":false,"excerpt":"La cohorte ANRS CO22 Hepather est constitu\u00e9e de patients atteints du virus de l'h\u00e9patite B \u2013 VHB et\/ou du virus de l'h\u00e9patite C chronique, aig\u00fce ou gu\u00e9rie. Il s'agit d'une \u00e9tude observationnelle multicentrique sous forme de partenariat public et priv\u00e9 avec un recueil prospectif de donn\u00e9es et la constitution de\u2026","rel":"","context":"Article similaire","block_context":{"text":"Article similaire","link":""},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":182,"url":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/espace-patients\/comment-est-organisee-linclusion\/","url_meta":{"origin":1043,"position":5},"title":"Comment est organis\u00e9e l\u2019inclusion","author":"admin_fchau","date":"24 janvier 2018","format":false,"excerpt":"Pour participer \u00e0 la cohorte ANRS CO22 Hepather, un patient doit respecter les crit\u00e8res d\u2019\u00e9ligibilit\u00e9 suivant\u00a0: Crit\u00e8res d'inclusion : Patients ayant ou ayant eu une h\u00e9patite B : - h\u00e9patite B chronique d\u00e9finie par un HBsAg, antig\u00e8ne de surface du virus de l\u2019h\u00e9patite B, positif pendant au moins 6 mois,\u2026","rel":"","context":"Article similaire","block_context":{"text":"Article similaire","link":""},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]}],"_links":{"self":[{"href":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/wp-json\/wp\/v2\/pages\/1043","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/wp-json\/wp\/v2\/comments?post=1043"}],"version-history":[{"count":2,"href":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/wp-json\/wp\/v2\/pages\/1043\/revisions"}],"predecessor-version":[{"id":2986,"href":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/wp-json\/wp\/v2\/pages\/1043\/revisions\/2986"}],"up":[{"embeddable":true,"href":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/wp-json\/wp\/v2\/pages\/165"}],"wp:attachment":[{"href":"https:\/\/triton.iplesp.upmc.fr\/hepather_ANRS\/wp-json\/wp\/v2\/media?parent=1043"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}